Looking for references to pA2

DSaussy dsaussy at aol.com
Wed Aug 10 17:34:15 EST 1994


In article <30h4bg$jj4 at mserv1.dl.ac.uk>, Sistemi Cellulari
<cell at cell.na.cnr.it> writes:

<<what exactly is pA2 (selective antagonist potency?)? what is the
equation(s) to 
estimate its value?  where can one read about it (other than Goodman and 
Gilman's Pharmacology textbook)?>>

You might also want to try Terry Kenakin's textbook "Pharmacologic
Analysis of Drug-Receptor Interaction" (2nd ed. Raven Press, 1993) for an
in depth explanation of pA2 and other methods of quantitative analysis of
ligand-receptor interactions.



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