Ewan ecm5f at darwin.clas.Virginia.EDU
Mon Dec 19 13:01:12 EST 1994


I am looking for an answer (or suggestions of source for an
answer) for two questions:

1.	Does orally taken citrate cross the blood-brain
barrier? (i.e is there a transport mechanism?)

2.	How long is citrate likely to remain in circulation
before being taken out by the liver?

[We'd like to give citrate to the level that could be produced
by glycolysis of 25g glucose, for memory studies, but the
conclusions will obviously be afected by the above...]

Thanks a lot!  email replies probably best unless there's
something of general interest?

Ewan McNay - ewan at

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