Course Announcement: Computation Neuroscience

David Remsen dremsen at
Fri Jan 14 09:29:41 EST 1994

Marine Biological Laboratory
Woods Hole, MA 02543
(508) 548-3705
contact: Dori Chrysler <dchrysle at>

For other course descriptions at the MBL:
gopher:    or...

----------------------- Methods in Computational Neuroscience

Methods in Computational Neuroscience
July 31- August 27, 1994; Application Deadline: April 15
This is an intensive, four-week lecture/laboratory course that addresses
issues relevant to computational neuroscience: the study of how the
biophysical and biochemical properties of neurons and synapses, together
with the architecture of neural circuits, produce animal behavior. The
course is designed to teach students to formulate questions about
computational aspects of a nervous system, to provide the analytical and
numerical simulation tools necessary to answer those questions, and to
allow students to interact with established investigators in this field.
The daily lectures provide a broad view of computational neuroscience,
while at the same time discussing in detail the interplay between models
and experiments for specific systems.  One series of lectures focuses on
the chemical and electrical dynamics of individual neurons and synapses. A
second series addresses the use of exact models of single cells, versus
reduced neuronal models, in the analysis of networks. A third series of
lectures considers development of nervous systems. A final series addresses
the detection, coding, and processing of external stimuli within nervous
systems with an emphasis on cooperative phenomena in cortex. Reviews on
areas of applied mathematics and biophycsics relevant to the above topics
are also presented.
The laboratory section of the course provides students with a unique
opportunity to advance their analytical and numerical simulation skills in
modeling specific aspects of nervous systems through tutorial projects,
together with an individualized modeling project. Each student is supplied
with a UNIX graphic-color workstation and state-of-the-art software
designed for the analysis of both single-cell dynamics and large network
properties. The packages include GENESIS and NEURON as well as DSTOOL and
PHASEPLANE.  In addition, the general mathematical analysis package
MATHEMATICA and the interactive graphics package IDL are available.
The course is designed for advanced graduate students, postdoctoral
fellows, and faculty members in a variety of disciplines, including
neurobiology, physics, electrical engineering, computer science, and
psychology. Familiarity with neurophysiology, basic mathematics i.e.,
calculus, linear algebra, and differential equations, and computer
programming, is highly desirable. Admission is limited to 23 students.
This course is supported in part by a training grant from the National
Institute of Mental Health and by a grant from the Office of Naval
Directors: David Kleinfeld and David W. Tank, AT&T Bell Laboratories,
Murray Hill, New Jersey.

Faculty: Lawrence Abbott, Brandeis University; Joseph J. Atick, Rockefeller
University; Mark Bear, Brown University; William Bialek, NEC Research
Institute; Ronald Calabrese, Emory University; Rodney James Douglas, MRC;
Bard Ermentrout, University of Pittsburgh; Scott Fraser, California
Institute of Technology; Apostolos P.Georgopoulous, University of
Minnesota; Charles Gray, University of California, Davis; Michael Hines,
Yale University; Roderick Jensen, Texas A & M University; John J. Hopfield,
California Institute of Technology; Christof Koch, California Institute of
Technology; Nancy Kopell, Boston University; Stephen M. Kosslyn, Harvard
University; John E. Lisman, Brandeis University; Rodolfo R. Llin‡s, New
York University Medical Center; John H. R. Maunsell, Baylor College of
Medicine; David A. McCormick, Yale University; Bruce L. McNaughton,
University of Arizona; John Rinzel, National Institutes of Health; Terrence
J. Sejnowski, Salk Institute; H. Sebastian Seung, AT&T Bell Laboratories;
Shihab Shamma, University of Maryland; Carla Shatz, University of
California, Berkeley; Gordon Shepherd, Yale University; Arthur Sherman,
National Institutes of Health; Karen Sigvardt, University of California,
Davis; Frederick Sigworth, Yale University; Haim Sompolinsky, Hebrew
University; and others to be named.
Tuition: $1550 (includes room & board)

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