als

Thomas P. Bleck tpb9k at galen.med.Virginia.EDU
Mon Jul 18 07:12:41 EST 1994


In article <40.761.3157 at channel1.com>,
Eliot Gelwan <eliot.gelwan at channel1.com> wrote:
>
>"Amyotrophic"refers to the fact that 
>there are *no* pathophysiological changes in the muscle tissue itself: 	
>	-a	"without"
>	-myo-	"muscle"
>	-trophic	"changes"

Actually, 'amyotrophy' simply means muscle wasting without any implication
of the cause or pathophysiology.  

(From Stedman's: 
amyotrophy (G. a- priv. + mys, muscle, + trophy, nourishment).  muscle wasting
or atrophy.)

The 'lateral sclerosis' part refers to the pathologic changes in the (lateral)
corticospinal tracts, which produce the upper motor neuron findings of the
disease.
--
Tom Bleck    (Thomas P. Bleck, M.D.)   tbleck at virginia.edu
Departments of Neurology and Neurological Surgery
University of Virginia School of Medicine
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