Alzheimers

Kurt A. Kistler kistler at a.chem.upenn.edu
Tue Jun 7 12:57:50 EST 1994


Hello all.  I just found this newsgroup, so I wanted to introduce
myself.  I am a graduate student in p-chem who in the last few years
has started getting involved with enzymatic simulations.  Recently
I started working on the AD problem, specifically AChE and its
reaction kinetics.  There has been a rumor in the literature that 
secretase, the enzyme that cleaves APP, may be a mutant form of AChE
in AD patients.  Does anyone know if this has actually been proven?
Any references?

I would very much like to discuss this stuff with anyone out there
who knows.  I have a good understanding of reaction physics as it 
applies to enzymes, so I might be of use, too.  I want to help
solve this problem of AD. 

--
Kurt


       ||                      |
    \\ || //                   |   Kurt A. Kistler
     \\||//                    |   University of Pennsylvania
     //||\\  The way of water. |   Department of Chemistry
    // || \\                   |   kistler at a.chem.upenn.edu
   // \||  \\                  |



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