Questions about GABA.

Fiberman william at neuro.usc.edu
Mon Oct 10 14:12:21 EST 1994


In article <36u79p$sfe at jhunix1.hcf.jhu.edu> fredlo at welchlink.welch.jhu.edu (C. FREDERICK LO) writes:
>
>In some cases, I believe that inhibition of GABA-A receptors may reduce 
>epileptic formation in the hippocampus.  Perhaps that's why people use 
>picrotoxin in their LTP experiments.
>
>-- Fred
>

I think picrotoxin is used in LTP experiments to block the action of GABAergic
interneurons, which would lessen the effect of LTP.

-fm





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