Question about the drug QUESTRAN

Dr. Alex aledain at receptor.pharm.uwa.edu.au
Thu Apr 6 21:12:43 EST 1995


>From: smith at ultranet.com (Louise Smith)
>Subject: Question about the drug QUESTRAN
>Date: Fri, 31 Mar 1995 19:33:03 -0500
>I'm seeking information about the drug QUESTRAN.  What does this drug do? 
>Is this drug currently being used to treat any conditions?  Is there any
>ongoing research efforts involving this drug?  What other names are there
>for this drug?
>Please reply to Louise Smith at smith at ultranet.com

Questran is cholestyramine resin, was originally used to control puritis, 
now used to lower concentration of plasma LDL-cholesterol. Used for treating 
hyperlipoproteinemia. Contraindicated in hpertriglyceridemia. Has been shown 
to reduce mortality of coronary heart disease (Lipid Research Clinics 
Program, J.A.M.A. 1984, 251, 351-364; and Ibid., 1984, 365-374.)

Data from Goodman & Gilman's The Pharmacological Basis of Therapeutics, 
8th edition, McGraw-Hill, p890-892.

cheers, Alex.

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Dr. Alex C. Le Dain              aledain at receptor.pharm.uwa.edu.au
Department of Pharmacology       Ph  (09) 346 3650
University of Western Australia  Fax (09) 346 3469
Nedlands, WA 6907
Australia.
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