POSTDOCTORAL POS\Molec. Neurobiol.

Andres Buonanno buonanno at
Mon Dec 4 11:16:15 EST 1995


   A position is presently available in the Unit on Molecular Neurobiology
at the National Institutes of Health to study the molecular mechanisms
regulating the plasticity of neural and muscle cells. The selective
regulation of different gene families by specific patterns of innervation,
which are modified during development and by experience, are largely
responsible for the plastic properties of neurons and muscles. The focus
of the laboratory has been to identify and characterize the transcription
factors that couple specific innervation patterns to the selective changes
in gene expression underlying plasticity. Multiple disciplinary approaches
are used in these studies, including: transgenic mice analysis, gene
knock-outs, general techniques for analyzing protein/DNA interactions and
promoter function, electrical stimulation of  cells in vivo and in
culture, immunohistochemistry, and in situ hybridization. Candidates are
required to have experience in molecular  biology.
   The laboratory is located in the department of Developmental
Neurobiology at the NIH campus in Bethesda, Maryland. There are
interactions with multiple laboratories studying different aspects of
neural development and neuroreceptor function. Candidates interested in
the position should send their curriculum vitae and the names of three
references to the address below.

Andres Buonanno, Ph.D.
Unit on Molecular Neurobiology
Building 49, Room 5A-38
National Institutes of Health
Bethesda, Maryland 20892-4480
Tel: (301) 496-0170
Fax: (301) 496-9939
Email: buonanno at

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