neural coding of behavior: evidence for precise timing of spikes ?
jan at neuroinformatik.ruhr-uni-bochum.de
Mon Dec 18 06:49:34 EST 1995
In article <4aa6o2$efd at eis.wfunet.wfu.edu> laubach at biogfx.neuro.wfu.edu (Mark
I want to point again that correlational analysis can not directly address
the issue of neural coding. That is, if one is to conclude that a pattern
of spike activity is a putative code for some neural process related to
stimulus or behavior, then one must show that the pattern of activity is
_predictive_ of the stimulus or behavior.
Hmm. The way I interpret this is: if the cross-correlation (or any other
signal processing of the neuronal signals) of two neurons alllows you to
distinguish stimuli that an old-fashioned PSTH does not, that
cross-correlation (or whatever) contains information the PSTH has
removed. Now, whether you can pinpoint the exact (statistical?) property of
the signals that contains that information is quite another matter.
Finally, I think that recent developments for large-scale parallel
recording (pioneered by our lab)
Would Krueger (Freiburg) and Eckhorn (Marburg) agree with you?
and for methods for the analysis of temporal variations by single neurons
and spatiotemporal variations by neural ensembles have led us to a new
"paradigm" for neurophysiology.
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