ANNOUNCEMENT: Four Day Visiting Fellowship Program on fMRI

Kathy M. O'Craven kmo at
Mon Dec 18 18:17:27 EST 1995


	    February 14-17, 1996 in Boston, Massachusetts

We are now accepting registration for the February session of the
4 Day fMRI program.  Registration is limited to 23 people and this limit has
been reached the last three times the course was given.  Future dates for 
the 4 Day fMRI program include June 12-15 and Oct 16-19,1996.

The pioneering work of MGH-NMR Center has elicited an explosion of research
in brain imaging.  While it has been known for almost 100 years that neural
activity causes localized changes in blood flow, the seminal work of Jack 
Belliveau, Ken Kwong, Bruce Rosen, and an extraordinary team of physicists, 
neuroscientists first demonstrated that magnetic resonance imaging can be 
used to monitor those changes in blood flow in humans. Because this
non-invasive technique permits many repetitions of experimental procedures 
on a single subject, it is rapidly becoming the method of choice for
 neuroscience research in functional brain mapping.

The purpose of the present course is to provide a serious introduction to 
this field.


Students will receive a firm grounding in the fundamentals of fMRI.  This will
include the basic physics of MR imaging, the biology and biophysics of the
hemodynamic responses to neural activity, data analysis (including both
exploratory and statistical analyses), stimulus presentation and response
recording in the context of high magnetic fields and electromagnetic pulses,
and the design of perceptual and cognitive experiments.

A special emphasis of the course will be the design, implementation, and
execution of  perceptual and/or cognitive experiments by the participants.
Participants will break into small groups to design their own fMRI experiments
These experiments will be executed, and the resulting data analyzed, on the
final day of the course.

The schedule shown below will be complemented by ample discussion time and
invited speakers.

The core faculty is drawn from the staffs of Massachusetts General Hospital,
Harvard University, Massachusetts Institute of Technology, Boston University
and Rowland Institute for Science.

The Institution

The MGH-NMR Center in Charlestown, which occupies nearly 20,000 square feet,
contains clinical, research, and educational MR activities of the Department
of Radiology of the Massachusetts General Hospital.  Functional MRI is
conducted at present using a 1.5Tesla GE scanner modified by Advanced NMR
Systems for Echo-Planar scanning.  It will be augmented by a 3.0 Tesla system
of similar design which will be devoted exclusively to brain imaging. There
are extensive computational facilities devoted both to fMRI and to more
general issues of brain imaging, such as segmentation and spectroscopy.
Computational facilities include networked Sun workstations, Silicon Graphics
Indigo and ONYX computers, and Apple Macintosh computers.

Typical Course Curriculum Outline: (taken from the most recent session).

WEDNESDAY      October 18

8:00-8:45      Introduction and Overview                          Robert Savoy
8:45-12:30     Session 1: The Machine 
     8:45-10:00   Principles of MR Imaging                         Bruce Rosen
     10:15-11:15  Image Contrast and Tradeoffs in fMRI        Robert Weisskoff
     11:15-12:30  Lunch and Discussion: Safety

1:30-5:00     Session 2: Experimental Design     
     1:30-2:30   Psychophysical Lab in the Magnet                 Robert Savoy
     2:30-3:00   PET, SPECT, and fMRI                              Scott Rauch
     3:15-4:15   Specific Design Strategies in fMRI Experiments  Chantal Stern
     4:15-5:00   Discussion

5:00-6:00     Walk to Pier for Deli takeout (or delivered)
6:00          Discussion; Preparation for "Sample" Experiment
7:00-9:00     Conduct "Sample" Experiment

THURSDAY     October 19

8:00-12:30     Session 3: Data Analysis
     8:00-9:15   Software Tools                                   Tom Zeffiro
     9:00-10:00  General Issues in Experimental Design        Nancy Kanwisher
     10:15-11:15 Comparing Brains                               David Kennedy
     11:30-12:00 Tracking Anatomy                                Nikos Makris
     12:00-1:30  Lunch and Discussion

1:30-5:30     Session 4: Data Analysis
     1:30-2:45   Data Analysis: Theoretical Overview               John Baker
     3:00-3:45   Data Analysis: Making Theory Concrete         Kathy O'Craven
     3:45-4:30   A Software System: MEDx                          Tom Zeffiro
     4:30-5:30   Discussion and Computers

6:30     Dinner in Atrium
8:00     Begin Design and Implementation of Experiments

FRIDAY     October 20

8:00-12:30     Session 5: Future
     8:00-9:30   Limits of Spatial and Temporal Resolution    Peter Bandettini
     9:45-10:15  Multi-Modality Imaging                         Jack Belliveau
     10:15-11:00 Principles of MR Imaging Revisited                Bruce Rosen
     11:00-12:30 Lunch and Discussion: Imaging Reprise

1:00-5:00     Session 6: Applications
     1:00-1:30   Presurgical Planning                           Brad Buchbinder
     1:30-2:30   Visual System                                    Roger Tootell
     3:00-5:00   Wine, Cheese, Posters, Computers

6:30     Dinner in Atrium
8:00     Complete Design and Implementation of Experiments
         Equipment Demonstrations

SATURDAY     October 21

8:00-5:00     Experiments; Data Analysis; Summary of Results; Discussion

Thomas J. Brady, M.D.         Director, MGH-NMR Center
Bruce R. Rosen, M.D., Ph.D.   Director, Center for Functional Neuroimaging
Robert L. Savoy, Ph.D.        Director, fMRI Education
Gerald Aaronson, Ph.D.        Director, NMR Development

Registration Form

Course fee of $1000 for the 4 day program, payable to MGH Visiting Fellowship
Program, must accompany registration and is refundable up to 30 days prior to
the session. Information on accommodations and activities in the Boston area
will be forwarded upon receipt of registration. A reduced rate of $600 is
available for graduate students with letter of verification from Department

Enrollment will be limited to 23 participants.  Please include an informal
statement describing your background (clinical, research, industrial, other),
your experience with MR imaging, and your experience with functional
neuroimaging.  This biosketch is used to help the faculty plan the course and
is normally distributed to the other course attendees, as well.  It should be
no more than 2 paragraphs in length.

Please E-mail the completed registration form and your background data and
mail your tuition to:

Dr. Gerald Aaronson
Director, NMR Development
MGH NMR Center
Building 149- 13th Street (2301)
Charlestown, MA 02129
Phone:(617) 726-5812
Fax:(617) 726-7422
E-mail:gaa at





Phone_____________________  FAX___________________


Preferred Date:              _______February 14-17, 1996

                             _______June 12-15, 1996

                             _______October 16-19, 1996

These 4-Day intensive courses, which are held at the MGH-NMR Center in
Charlestown, Massachusetts, are limited to 23 people to permit ample
time for laboratory work, discussion, and extensive
question-and-answer sessions.  These 4-Day courses are not to
be confused with the one-time, 2-Day fMRI Workshop scheduled for June
16-17, 1996.  The 2-Day fMRI Workshop (called "fMRI2Day") will be held
at the Boston Sheraton Hotel, in conjunction with the Second
International Conference on Functional Mapping of the Human Brain.
(This conference runs from the evening of June 17-21, in the same
hotel.)  The fMRI2Day Workshop will consist of one day of lectures
(with essentially no time for questions) followed by a day of panel
discussions on research topics related to fMRI.  Attendance at the
fMRI2day Workshop will be unlimited (except that the lecture room
holds no more than 1200 people).  Attendees may sign up for one or
both days.

More information about the fMRI2Day Workshop and the Second International
Conference on Human Brain Mapping can be obtained via the world wide web at (fMRI2Day Workshop)  (Conference on Brain Mapping)

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