neural coding of behavior: evidence for precise timing of spikes ?

[Ron Blue]

On 21 Dec 1995, Jan Vorbrueggen wrote:
> In article <4b536l$baq at eis.wfunet.wfu.edu> laubach at biogfx.neuro.wfu.edu (Mark
> Laubach) writes:
> 
>    When are you going to distinguish the stimuli?  After looking at all the
>    trials on average?
> 
> No, potentially during/immediately after the stimulus.
> 
>    My point was that we need trial-by-trial predictors for analyzing neuron
>    activity.
> 
> I understood that.
> 
>    A cross-correlation is nothing more than a correlational measure between
>    time-series and a correlational measure is not a predictor for
>    trial-by-trial classification.
> 
> Ah. You seem to be thinking of using the cross-correlation of one cell's
> activity during different trials - that's not what I meant. I was talking of
> the cross-correlation of two cells simultaneously active, which you (or
> another cell) can compute on-the-fly, as it were. This _does_ enable you (or
> that other cell) to distinguish the two stimuli as they are occuring.
> 
> 	Jan
correlations computed on-the-fly sounds interesting.  But to do this
it seems that a time measure should be specified in advance.  At this
time I suspect that theta may be the underlying basic frequency or
reference wave.  It is likely to be different for different functions.
So if a spike recording can be observed during one half of a cycle it 
would be considered to be on for the area being observed.  Correlations 
from such research may lead to success.  Ron Blue