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Info Wanted on Landau Kleffner Syndrome

Portia Iversen portia at netcom.com
Mon Jun 12 21:24:23 EST 1995

I replied earlier that LK is a newly discovered disorder - I stand
corrected! It was discovered in 1957.  Here are a few references:

Soprano AM, et al, 
Acquired epileptic aphasia: Neuropsychological follow-up of 12 Patients, 
Pediatric Neurology, Oct. 1994  (a study of 12 LK patients)

Tharpe AM, et al, 
Landau-Kleffner syndrome: Acquired Epileptic Aphasia in Children, 
Journal of American Academey of Audiology, March 1994

Marien P, et al
Some Controversies About Type and Nature of Aphasic Symptomology in
Landau=Kleffner's Syndrome: a CAse Study,
Acta Neurol Belg 1993;93 (4):183-203

Interestingly, it has  been found that  some autistic children who do NOT
fit the LK profile may benefit from a course of steroids as is sometimes
used in LK. 

In article <3r5hvq$ate at riscsm.scripps.edu>, Wendy Jones
<jones at crl.ucsd.edu> wrote:

> I too have questions about Landau Kleffner Syndrome, and would 
> appreciate any information that you may have.
> From what I have heard so far, Landau Kleffner is diagnosed with an 
> abnormal sleep EEG.  Children with it characteristically have "normal" 
> language development prior to the onset of siezures, at which time their 
> language development stops.  Apparantly there are drugs (steroids?) that
> can boost the development of language.
> A parent of a patient gave me this information, but I have thus far not 
> followed it up.  Please let me know if you have further details.
> Wendy Jones
> The Salk Institute for Biological Studies
> jones at crl.ucsd.edu


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