Electrochemistry, paleobiology, neurophysiology, evolution & aging

grokelly at delphi.com grokelly at delphi.com
Fri Mar 10 13:34:23 EST 1995

	The paper "Biology, Bioelectricity, and the Nervous System" 
deals with the connections and interrelatedness of paleo- and 
neurobiology, evolution and vertebrate speciation, biochemistry, 
electrochemistry and electrodynamics.  It posits the same 
electrodynamics are operant at the cell's nucleus as the level 
of the cell's so-called 'behavior', or the systemic level dealing with 
the behavior of the organism that is composed of the cells.  In 
presenting this model the paper discusses in detail the flaws in 
prevalent models of neuronal functioning, in particular that of the 
ionic channel school of Eccles, Hodgkin, and Huxley as presented by 
Bertil Hille (Ionic Channels of Excitable Membrane) and John Koester 
(Principles of Neural Science) which seeks to account for neuronal 
functioning in terms of electricity rather than electrochemistry.
	The paper suggests, by its proposed model, a new treatment 
involving 'galvanic revivification' to treat chronic and degenerative 
disorders.  The treatment does this by acting upon cellular 
chemistry through electrolytically triggered changes similar to 
those affected by the nervous system.  The paper presents a short 
history of electromedicine and understanding of the phenomenon of 
electricity going back as far as the 18th century, and proffers a 
vision of the nervous system that is based on considerations of 
chemistry and polarity.  This vision is concordant with current 
understanding of the origins of cellular life, and paleobiology.  Yet is 
highly critical of clinical neurology which, being founded on the 
ionic channel school's model, is noticeably deficient in effective 
treatment for any neuromuscular, nervous, or psychiatric disorder.
	With regard to paleobiology, the paper is organized as a 
criticism of the genetic gradualism of Ernst Mayr and its failure to 
take into consideration the systemic changes manifested by 
increased numbers of emergent nerve terminals found on creatures 
as one moves out onto the tree of life.  For Mayr chemistry does not 
favor life's origins which are thought of as requiring unique and rare 
conditions.  For the electro-organic chemist, given the early 
atmospheric conditons of the earth, the orgins of life are a matter 
of course, and the evolution of that life from prokaryotes to 
eukaryotes to multi-celled organisms possessing the power of 
locomotion and nervous systems is just the result of building on the 
same basic electrochemistry of the cell.  The paper suggests that 
the aging and deterioration of the cell, as the aging and degeneration 
of the cellular organism, are also related in this way;  and that by 
maintaining the cell's membrane voltage and reversing systemic 
degradation through electrolytic intervention one can effectively 
stop and reverse the effects of aging.  
	Currently there are two general schools of thought with regard 
to aging.  One school would have it that aging is a result of genetic 
programming;  the other insists that it is the result of systemic 
deterioration.  The paper, by relating intracellular chemistry and 
systemic functioning to electrochemistry, suggests that introducing 
a negative electrical charge at the site of nerve terminal synapses 
acts to simulate strong CNS functioning (which has a powerful 
restorative effect post-synaptically), and to penetrate the nervous 
system antidromically (restoring and maintaing cell membrane 
voltages for prolonged cell nucleus functioning, including genetic 
	The paper is 60 pages long in E-mail format, that is, without 
italics, underlining or font changes, super or subscripts.  This does 
not affect the message.  I am looking for those who might be 
interested to discuss the ideas therein presented.  E-mail Dr. 
Galvano at grokelly @delphi.com for a copy.

					Dr. Galvano

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