Alzheimer's Disease and diagnosis w/ tropicamide (fwd)

washington ryan rwashi1 at gl.umbc.edu
Mon May 1 19:53:03 EST 1995


I'm interested in knowing the results of your experiment. Have your 
patients reacted in the manner in which you've predicted or not???


---------- Forwarded message ----------
Date: 28 APR 1995 09:14:30 -0400 
From: x011 at Lehigh.EDU
Newgroups: bionet.neuroscience
Subject: Re: Alzheimer's Disease and diagnosis w/ tropicamide 

In article <D7noz6.K4M at midway.uchicago.edu>, rout at quads.uchicago.edu (Mark Routb
ort) writes:
>In article <3ne7ej$ge6 at synapse.bms.com>,
>Rick Belval <belval at synapse.bms.com> wrote:
>>In the 11-Nov-94 issue of Science, Mass. researchers presented evidence
>>indicating that AD patients are more sensitive to the pupil-dilating and
>>acetylcholine-blocking drug, tropicamide.  Has anyone seen any follow-up
>>articles in this area of study?
>>Rick Belval
>>belval at synapse.bms.com
>>>>>>>>>>>>>>>>>> C U T >>>>>>>>>>>>
We give Alzheimer's patients medicine in an effort to increase their
acetylcholine production.  They continue to decline.

Perhaps, we should do the opposite.

Give medicines to block acetylcholine transmission in the brain.  The
brain should try to conteract the medicine by growing new acetylcholine
connections and reduce the process of erasing acetylcholine processing
sites.  When we take the medicine away a month later the patient should
be preforming at significantly higher levels of cognitive functions.
Ron Blue x011 at lehigh.edu





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