In <morin.13.00118B83 at neuromotri.u-bordeaux.fr> morin at neuromotri.u-bordeaux.fr (Didier Morin) writes:
>I worry about my in vivo experiments on the rabbit. The anaesthesia that I use
>(pentobarbital) induces an inhibition of locomotor activities during 6 hours.
>However, the time surgery lasts up to 4 hours. Then, I need to reduce the time
>effect of the anaesthesia. Could anyone know an other anaesthetic (except
>halothane, fluothane or any that kind of anaesthetics) able to satisfy my
>Thank you in advance,
>E-mail : morin at neuromotri.u-bordeaux.fr
Well I use Saffan (steroid anaesthetic, mixture of alphadolone and alfaxalone)
on rabbits and find it excellent. The animals wake from anaesthesia very
quickly: 15-20min. Saffan has a plasma half life of approx 7 min. It is
much more expensive than pentobarbital. It needs to be given under continuous
Another possibility that I have ot tried is propofol. I don't know much
about it, but it is injectable (I believe continuous infusion). It also
email me if you want to know my protocol using Saffan.
jaimiep at physiol.su.oz.au