QUESTION regarding autoreceptor affinity

Tim Teyler tjt at
Wed Sep 13 10:40:09 EST 1995

Is it generally true that autoreceptor affinities are higher than 
postsynaptic receptor affinities?  If this is generally true it seems odd 
that feedback inhibition would start to kick in BEFORE transmitter 
binding to the postsynaptic receptor occurs.

Tim Teyler

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