Prions? CJD/BSE Connection...

David Cassarino dsc9w at avery.med.Virginia.EDU
Wed Apr 3 21:05:54 EST 1996


dcurtis at hgmp.mrc.ac.uk  writes:
> lenin at dircon.co.uk (Chris Slater-Walker) wrote:
> 
> >Apart from pathological cases or examples in extremis (e.g. the Andes 
> >plane crash) there is absolutely no evidence of 'normal' cannibalism 
> >anywhere on earth. The transmission of kuru is not by the eating of human 
> >brains but by the practice employed by those contracting this disaease of 
> >exhuming their dead after a period of burial, and emptying the cranial 
> >cavity of brain material by hand; the disease being transmitted through 
> >small cuts in the skin.
> 
> You could perhaps cite references for this account? The whole
> scientific establishment believes kuru to have been transmitted by
> ingestion, not innoculation. Women had higher rates because they got
> left with the brains and offal, while men ate the muscle which had a
> lower concentration of infective material.
> 
> 
> 
> 
> Dave Curtis
> http://www.gene.ucl.ac.uk/~dcurtis
> 
The only way to get CJD from ingestion of prions is via
innoculation (ie, if you have cuts in your mouth or
esophagus).  As proteins, prions are degraded to AAs in the stomach,
and thus do not pose a significant threat in the normal GI
system.  
    
-- 
David S. Cassarino              "The mind is not a vessel to be filled
MSTP 2nd Year                    but a fire to be kindled."               
UVA School of Medicine           -Plutarch
dsc9w at virginia.edu          



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