Prions? CJD/BSE Connection...

Dave Curtis dcurtis at hgmp.mrc.ac.uk
Sat Apr 6 20:10:14 EST 1996


dsc9w at avery.med.Virginia.EDU (David Cassarino) wrote:

>The only way to get CJD from ingestion of prions is via
>innoculation (ie, if you have cuts in your mouth or
>esophagus).  As proteins, prions are degraded to AAs in the stomach,
>and thus do not pose a significant threat in the normal GI
>system.  

I'm sorry, but this is completely untrue. Prion diseases certainly can
be contracted by ingestion. Most proteins are digested, but small
quantities of few foreign proteins do enter the circulation intact.


Dave Curtis
http://www.gene.ucl.ac.uk/~dcurtis




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