Bromocriptine and Blood Brain Barrier

[Laurie Davison]

Hi!
   Can anyone out there tell me whether bromocriptine mesylate crosses 
the blood-brain barrier? If "no", could you suggest another D2 agonist 
that may be useful. I'm working with mares, so anything causing 
side-effects that may cause them to become unmanageable is strictly 
"out"! Thanks in advance for your help.

                                           Laurie Davison
                                           Gluck Equine Research Center
                                           ldavison at ukcc.uky.edu