Bromocriptine and Blood Brain Barrier

[Sandra L Wegert]

>    Can anyone out there tell me whether bromocriptine mesylate crosses 
> the blood-brain barrier? If "no", could you suggest another D2 agonist 
> that may be useful. I'm working with mares, so anything causing 
> side-effects that may cause them to become unmanageable is strictly 
> "out"! Thanks in advance for your help.

Is this the same bromocriptine salt given to humans?  It's given for 
Parkinson's and pituitary dysfunction, so it would seem that it does get in.

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sandraw at U.Arizona.EDU