Pathway specificity of hippocampal LTP
Sandra Pena De Ortiz
spenadeo at lonestar.jpl.utsa.edu
Thu Aug 15 11:25:34 EST 1996
On 13 Aug 1996, Hannah Dvorak wrote:
> LTP in the hippocampus is supposed to be pathway specific. If two
> independent sets of Schaffer collaterals are stimulated, and one is
> tetanized to induce LTP, the other pathway is unaffected or is
> depressed (heterosynaptic LTD). All the papers I've seen describing
> this phenomenon use extracellular field recordings to demonstrate
> this pathway specificity. Does anyone know of a reference showing
> independent potentiation of pathways converging on a single neuron,
> i.e. using intracellular or whole-cell recording?
> Hannah Dvorak
> Division of Biology 216-76
> California Institute of Technology, Pasadena, CA 91125
There is a paper Nature that came out about 2 or 3 months ago by Derrick
and Martinez showing associative heterosynaptic Mossy Fiber LTP in vivo.
Sandra Pena de Ortiz, Ph.D.
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