Pathway specificity of hippocampal LTP

Hannah Dvorak hdvorak at cns.caltech.edu
Fri Aug 16 18:36:37 EST 1996


In article <Pine.SOL.3.91.960815112329.6618A-100000 at lonestar.jpl.utsa.edu>, 
spenadeo at lonestar.jpl.utsa.edu says...
>
>
>
>On 13 Aug 1996, Hannah Dvorak wrote:
>
>> LTP in the hippocampus is supposed to be pathway specific.  If two
>> independent sets of Schaffer collaterals are stimulated, and one is
>> tetanized to induce LTP, the other pathway is unaffected or is
>> depressed (heterosynaptic LTD).  All the papers I've seen describing
>> this phenomenon use extracellular field recordings to demonstrate
>> this pathway specificity.  Does anyone know of a reference showing
>> independent potentiation of pathways converging on a single neuron,
>> i.e. using intracellular or whole-cell recording?
>> 
>> --
>> Hannah Dvorak
>> Division of Biology 216-76
>> California Institute of Technology, Pasadena, CA 91125
>> 
>> 
>> 
>---------------------------
>There is a paper Nature that came out about 2 or 3 months ago by Derrick 
>and Martinez showing associative heterosynaptic Mossy Fiber LTP in vivo.
>
>Sandra Pena de Ortiz, Ph.D.
>UTSA

Thanks, but I was specifically looking for a paper showing independent
potentiation of one of two pathways converging on the same neuron
(recorded intracellularly), not just a population of neurons.  I did
finally find one:  Kelso et al. 1986, PNAS 83:5326-5330.

- Hannah

-- 
--
Hannah Dvorak
Division of Biology 216-76
California Institute of Technology, Pasadena, CA 91125




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