Neuron charging
Michael Michalchik
michalch at blue.weeg.uiowa.edu
Thu Aug 29 12:59:59 EST 1996
Hi you need to get a good book on neuroscience such as:
The physiology of excitable cells, or the principles of neuroscience
(preferably both)
and look up the following topics:
Temporal summation
Spatial summation
Post tetanic potentiation (PTP)
Long term potentiation (LTP)
"axon hillock" or "zone of initiation"
refractory period
the action potential
excitatory transmission
inhibitory transmission
EPSP
mEPSP
IPSP
mIPSP
Long term depression (LTD)
Time constant. tau
Spatial contant. lambda
Electrical and chemical gating of channels
I am not trying to overwhelm you. Most of these subjects shouldn't be
too hard if you have an electronics background. Some of them you will
only need a cursory glance at to see what is importent to you.
The short answer to your question is yes. But the charge disperses
through the volume of the cell and leaks out through the mebrane, and
gets pumped out actively. There are well developed equations that
accurately predict the dynamics of cells with simple structues. You
should also know that there are enhancements in transmission associated
with synapses that have been active. This is not just the neural
learning phenomena that you are familiar with, but refelect the fact the
the presynaptic neuron will release more transmitter on its second shot
due to the accumulation of release related chemicals in the presynaptic
cell.
Your idea is an interesting one, poke around a bit before you decide
what is importent.
Michael Michalchik
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