dentate granule cell addition

Simon Schultz schultz at axp2.cns.ox.ac.uk
Wed Jul 24 11:15:17 EST 1996


In 1982 it was reported that in rats, dentate granule cells continued to 
be added to the hippocampus over the whole first year of life (no results 
for thereafter) (Bayer et al 1982, Science 218:890-892). Does anyone know 
of any evidence since then that this is a real phenomenon, and whether it 
transfers across species?

West and Gunderson (1989, J. Comp. Neurol. 296:1-22) found no evidence of 
continual addition of granule cells in the human, although there were 
only 5 specimens and they started at just under 50 years.

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                          Simon R. Schultz                       
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