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dentate granule cell addition

Sandra Pena De Ortiz spenadeo at lonestar.jpl.utsa.edu
Thu Jul 25 13:02:33 EST 1996

On Wed, 24 Jul 1996, Simon Schultz wrote:

> In 1982 it was reported that in rats, dentate granule cells continued to 
> be added to the hippocampus over the whole first year of life (no results 
> for thereafter) (Bayer et al 1982, Science 218:890-892). Does anyone know 
> of any evidence since then that this is a real phenomenon, and whether it 
> transfers across species?
> West and Gunderson (1989, J. Comp. Neurol. 296:1-22) found no evidence of 
> continual addition of granule cells in the human, although there were 
> only 5 specimens and they started at just under 50 years.
> -----------------------------------------------------------------------
>                           Simon R. Schultz                       
> Department of Experimental Psychology                             also:
> University of Oxford                             Corpus Christi College
> South Parks Rd., Oxford OX1 3UD                          Oxford OX1 4JF
> Phone: +44-1865-271419  Fax: +44-1865-310447 Home: 66119
>                 http://www.mrc-bbc.ox.ac.uk/~schultz/
> -----------------------------------------------------------------------
There was a paper in this years J. of Neuroscience on Granule cell 
Neurogenesis in the hippocampus.  I don't have the reference with me though.


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