Looking for decarboxylase

Pierre AUBINEAU pierre.aubineau at hippocrate.u-bordeaux2.fr
Thu Jan 16 06:51:40 EST 1997


I'm presently designing a new research protocol which supposes that I can
visualize histologically (L.S. confoc. microsc., or electron mic.) the
cellular localization of the first step of serotonin sythesis, i.e., 5-HTP.
Since, to my knowledge, no Ab exist against 5-HTP, the easiest way seems to
me to transform ex-vivo the 5-HTP into 5-HT by the action of a L-amino acid
decarboxylase. Could tyrosine decarboxylase be efficient for this purpose ?
Does it exist a more specific decarboxylase available (commercially or
not).
Thank you in advance for your help.
 
pierre.aubineau at hippocrate.u-bordeaux2.fr



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