Q: Sleepy leg

Alan Fried albe at worldnet.att.net
Sat Jan 25 09:43:16 EST 1997

Anthonie Muller <awjm at holyrood.ed.ac.uk> wrote:


>I have the same problem, and I am also a bit worried.
>I attribute it to my lack of exercise since I left Holland two years ago;
>here in the UK it is almost suicidal to go by bike (the lack of exercise
>would impair my circulation). 

>My explanation it that lack of oxygen causes a decrease of ATP, which in 
>turn makes it impossible to keep up the nerve membrane potential,
>leading to an action potential which makes you feel the local absence of

>I also know that at low oxygen concentrations oxygen is not completely
>reduced, leading to the formation of free radicals, which are highly
>damaging. Vitamins C and A might however protect against free radicals. 

Hi Anthonie

Very intense explanation. But I don't beleive it is quite that complicated. It's just a matter of blood flow being
obstructed. Once you move around it comes back again. I find your hypothesis interesting though and it does make sense that
this may in fact occur if the cells do not receive oxygen from the blood..

Take care


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