Q: Sleepy leg

Sven Haul Sven.Haul at uni-duesseldorf.de
Tue Jan 28 15:19:04 EST 1997


>>Anthonie Muller <awjm at holyrood.ed.ac.uk> wrote:

>>My explanation it that lack of oxygen causes a decrease of 
>>ATP, which in 
>>turn makes it impossible to keep up the nerve membrane 
>>potential,
>>leading to an action potential which makes you feel the 
>>local absence of
>>oxygen.

This seems unlikely to mee. The cell tries to keep up the 
membrane potential as long as possible. So if the ATP 
shortage is prominent enough to cause a drop of membrane 
potential by about 30 mV other damages should have occured 
before, and should be noticeable afterwards.

regards,
	Sven

--
Sven E. Haul                             Heinrich-Heine-University
Institute of Neurophysiology             Duesseldorf, Germany
http://www.uni-duesseldorf.de/WWW/MedFak/Neurophysiologie/haul.htm



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