ethanol

Serge Helfrich s.helfrich at mailhost.net
Thu Jan 30 08:41:38 EST 1997


> ---- Article -------
> From: "Jacques Stephane Philippe" <JacquesPhilippe at msn.com>
> Subject: ethanol
> Newsgroups: bionet.neuroscience
> Date: Wed, 29 Jan 1997 15:17:56 -0800
> 
> Does EtOH decrease the inhibition of cAMP?

"Acute exposure to ethanol causes increased cAMP production whereas
chronic exposure results in heterologous desensitization. These changes
are due to accumulation of extracellular adenosine resulting from
inhibition of adenosine uptake into cells."

Gordon AS, Diamond I, Adenosine mediates the effects of ethanol on the
cAMP signal transduction system. Alcohol & Alcoholism, suppl.
2:437-441,1993.

Serge
-- 
===========================================================
Serge Helfrich           |
s.helfrich at mailhost.net  |  http://www.xs4all.nl/~helfrich/
===========================================================


-----
<1>
Authors
  Yoshimura M.  Tabakoff B.
Title
  Selective effects of ethanol on the generation of cAMP by particular
  members of the adenylyl cyclase family.
Source
  Alcoholism, Clinical & Experimental Research.  19(6):1435-40, 1995
Dec.

<2>
Authors
  Yang X.  Diehl AM.  Wand GS.
Title
  Ethanol exposure alters the phosphorylation of cyclic AMP responsive
  element binding protein and cyclic AMP responsive element binding
activity
  in rat cerebellum.
Source
  Journal of Pharmacology & Experimental Therapeutics.  278(1):338-46,
1996
  Jul.

<3>
Authors
  Kelly E.  Harrison PK.  Williams RJ.
Title
  Effects of acute and chronic ethanol on cyclic AMP accumulation in
  NG108-15 cells: differential dependence of changes on extracellular
  adenosine.
Source
  British Journal of Pharmacology.  114(7):1433-41, 1995 Apr.




More information about the Neur-sci mailing list