blocking axonal transport in rats

Eriko Terao terao at
Mon Jun 2 06:24:41 EST 1997

We are currently trying to block axonal transport in the facial nerve of
adult rats. We have tried both vincristine and vinblastine at different
concentrations (0,15 et 0,05 mM) as drugs. However, either we have no
effect, or we get massive demyelinations and probably chemical axotomy as

Has anyone experience with these techniques ?

Thank you very much

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