blocking axonal transport in rats

Eriko Terao terao at bani.ucl.ac.be
Mon Jun 2 06:24:41 EST 1997


We are currently trying to block axonal transport in the facial nerve of
adult rats. We have tried both vincristine and vinblastine at different
concentrations (0,15 et 0,05 mM) as drugs. However, either we have no
effect, or we get massive demyelinations and probably chemical axotomy as
well.

Has anyone experience with these techniques ?

Thank you very much



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