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brain cell regeneration

Alonzo Ross Ross at SCI.WFBR.EDU
Wed May 14 07:42:53 EST 1997

There is a great deal of research being done on CNS stem cells
which have the potential of generating new neurons, astrocytes
and oligodendrocytes. There are two types of approaches. The
first utilizes stem cells grown up from the brain, generally
using FGF or EGF as mitogen. The second uses reversibly
transformed cell lines. Here are a few review articles:

Gage et al. Annu. Rev. Neurosci. 18, 159-192 (1995).
Morrison et al. Cell 88, 287-298 (1997).
Weiss et al. TINS 19, 387-393 (1996).
Stemple et al. Neuron 18, 1-4 (1997)

These are good reviews well worth the time.

Alonzo Ross

>What research is being done in regenerating dead brain cells?  Is any
>progress being made?
>	Thank you,
>	   Paul Ostrof
>	   paulo at frii.com

Alonzo H. Ross                  508-842-8921
Worcester Foundation            FAX 508-842-9632
222 Maple Ave.                  Ross at SCI.WFBR.EDU
Shrewsbury, MA 01545            http://www.wfbr.edu

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