UNITED MEDICAL AND DENTAL SCHOOLS OF GUY'S AND ST THOMAS'S HOSPITALS
(University of London)
Development of an in vitro model to study the
neurotoxic mechanisms of ecstasy.
Postdoctoral Research Fellow
Biochemical Neuropharmacology Group
UMDS Division of Biochemistry & Molecular Biology, Guy
Salary 15,159 (GBP) plus London Weighting Allowance 2,134 (GBP)
A postdoctoral position funded by the Medical Research Council is
available immediately for one year to study how the drug of abuse
methylenedioxymethamphetamine (MDMA, ecstasy) is toxic to serotonin
neurones. The project involves the development and use of cell-lines
transfected with the serotonin transporter. The successful applicant will
use pharmacological and biochemical techniques to study cell death, and
toxicity caused by ecstasy in vitro, with the aim to identify the intracellular
mediators of toxicity . The successful applicant will have recently gained a
PhD or submitted a PhD thesis in a suitable area such as pharmacology,
molecular biology, neuroscience, cell biology or biochemistry and have
demonstrable experience of some of the techniques to be used in this project.
Training will be provided in all techniques, as necessary. The postholder
will be based in Dr Robert Williams' laboratory at Guy's Hospital.
To obtain a job description, send a stamped addressed envelope (A4 size)
to the Personnel Department, UMDS, St Thomas's Hospital, London SE1 7EH,
G/BIO/RO/266. For further details about the project or the research
environment at UMDS contact Dr Marcus Rattray (m.rattray at umds.ac.uk)
or Dr Robert Williams (r.williams at umds.ac.uk).
Letters of application should include a c.v. and the names, addresses,
e-mail addresses and phone numbers of two referees, and be sent to
Dr M. Rattray, Biochemical Neuropharmacology Group,
UMDS Division of Biochemistry and Molecular Biology, Guy's Hospital,
London SE1 9RT. Applications must be received by 5th November 1997, with
short-listed applicants notified within 2 weeks of the closing date.
We regret that unsuccessful applicants will not be contacted.
EQUALITY OF OPPORTUNITY IS SCHOOL POLICY