A question re LTP (was a dyslexic mistake should be LTP) during opioid-mediated or (otherwise mediated) consciousness-cancelling anaesthesia

F. Frank LeFever flefever at ix.netcom.com
Sun Dec 20 21:37:59 EST 1998

No point reading the article if you're going to blur the distinctions
between single-cell studies and whole-brain studies.  Even if one were
to equate LTP and "memorization" (which would be a serious error in and
of itself), gating inputs to a single cell is similar to what you
suggest for the whole brain only on a metaphorical sense (and maybe not
such a good metaphore at that). 

There are, of course, the demonstrations of procedural learning and/or
both classical and operant conditioning in amnestic patients, who learn
with no memory of learning, but that is on a different level of
description and FAR, FAR from the phenomenon you describe.

Surely you must know this.

Are you SHITting us again?

F. Frank LeFever, Ph.D.
New York Neuropsychology Group

In <367c9ba8.0 at pink.one.net.au> "\"Sir Knowitall\""
<for.spam.reasons.peel.away.until.only.fellin.remains at one.net.au>
>"Sir Knowitall" wrote in message <367c99df.0 at pink.one.net.au>...
>>Hello all!
>>I can remember having read one science-journal report about a
>>laboratory experiment that found that a single neuron was able to
>>memorisation changes towards "Long Term Potentiation" as a result of
>>impact of signals from ONLY one out of two or more of the types of
>>excitatory fibres that it was targeted by, even while the other
type(s) of
>>excitatory fibre-input was pre-synaptically gated (i.e. artificially
>>as part of the experiment).
>>My problem is that I have forgotten, and can not find my most likely
>>permanently lost scribbled-down notes about, precisely what was
>>where and by whom.
>>Can somebody who knows please re-supply me with answers to who did
>>experiment or a closely similar experiment, and when and where was
>>result published?
>>[This reference would go towards further supporting/substantiating
>>notion (already backed by other less nitty-gritty observations) that
>>memory/learning imprints can accumulate whilst the individual in whom
>>experience is being recorded is kept unconscious by his/her own
>>pre/sub-consciously self-regulatory gating reflexes.
>>It is of relevance to the transformation (or as if "putting") of
>>Hibernation Imploring Type (life-)Situations" into a correspondingly
>>specific insidious states of "Conditioned-in Unconsciously Retained
>>type) Stressors Effecting (Spin-off-)Symptoms".]
>>Thanks in advance,
>>Peter F

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