Parkinson's disease & rigidiy

Renato Cocchi MC7057 at MCLINK.IT
Wed Feb 25 16:50:43 EST 1998


> From: Marcello Spinella <optimism32 at hotmail.com>
> Organization: EarthLink Network, Inc.
> Subject: Parkinson's disease and rigidity
> 

> If Parkinson's disease involves rigidity, why isn't baclofen
> effective to treat it?
 
 Perhaps  because  Parkinson's rigidity is  a  dopamine-related 
symptom and  baclofen is a B-GABAergic agonist. 
 The  fact  that baclofen is an antispastic  is  insignificant: 
What  seems  the  same symptom can  be  produced  by  different 
breakdowns (eg. haemophilia).

 Renato Cocchi MD



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