Parkinson's disease & rigidiy
MC7057 at MCLINK.IT
Wed Feb 25 16:50:43 EST 1998
> From: Marcello Spinella <optimism32 at hotmail.com>
> Organization: EarthLink Network, Inc.
> Subject: Parkinson's disease and rigidity
> If Parkinson's disease involves rigidity, why isn't baclofen
> effective to treat it?
Perhaps because Parkinson's rigidity is a dopamine-related
symptom and baclofen is a B-GABAergic agonist.
The fact that baclofen is an antispastic is insignificant:
What seems the same symptom can be produced by different
breakdowns (eg. haemophilia).
Renato Cocchi MD
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