Support of Explanation of Obstructive Sleep Apnea

kkollins at pop3.concentric.net kkollins at pop3.concentric.net
Sun Nov 29 00:31:14 EST 1998


I assure you, that in my case, the hours I keep have everything to do with
whether or not I've got to get up, in the morning... not having to, as during
this Thanksgiving weekend here in the U.S., is some of my Favorite-Stuff... I
take advantage of the "open-endness" inherent in it to just keep-working without
regard for the "clock". ken collins

James Howard wrote:

> Support of Explanation of OSA
>
> I developed an explanation of obstructive sleep apnea (OSA), based on my
> explanation of sleep.  My explanation of OSA suggests that testosterone
> worsens OSA.  The following quotation, which I just discovered, directly
> supports my theory of OSA.  I invite you to read it as “Testosterone and
> Sleep: Support for Sleep Theory” at http://www.naples.net/~nfn03605/ on the
> web.
>
> James Howard
> Fayetteville, Arkansas, U.S.A.
>
> Mayo Clin Proc 1998 Mar;73(3):246-8
> “Obstructive sleep apnea due to endogenous testosterone production in a
> woman”
> Dexter DD, Dovre EJ
> Department of Neurology, Midelfort Clinic, Eau Claire, Wisconsin 54701, USA.
>
> “Obstructive sleep apnea (OSA) is a common condition characterized by
> snoring, recurrent episodes of cessation of breathing (obstructive apneas),
> disrupted sleep, and excessive daytime somnolence. Associated serious
> complications are hypertension, increased risk of heart disease, stroke, and
> increased susceptibility to industrial and motor vehicle accidents. OSA is
> considerably more common in men than in women. In postmenopausal women, the
> incidence of OSA increases. These factors suggest that reproductive hormones
> have a role in the cause of OSA. Treatment with testosterone has been
> reported to cause OSA in men, and exogenous androgen administration has been
> reported to cause OSA in one woman. In a review of the English literature,
> we found no previous reports of OSA that was induced by endogenous
> testosterone in women. Herein we describe a nonobese 70-year old woman with
> clinically significant OSA and a benign testosterone-producing ovarian
> tumor. After successful removal of the tumor, her OSA resolved, and her
> testosterone level normalized. This unique case supports the theory of male
> hormonal (testosterone) influence in the OSA syndrome.”






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