IV pentamidine : unknown neurological side effect ?
gnegro at vtx.ch
Mon Oct 12 18:34:58 EST 1998
Two years and a half ago, I was treated for a PCP with IV pentamidine,
because I was allergic to trimatoprim-sulfamethoxazole.
After one week treatment, I was left paralyzed down my right side, had a
paresia of all my body and could hardly speak; because of a partial necrosis
of my cerebral trunk.
What was the reason ? The HIV, a loss of vitamin B, or IV pentamidine ?
Pentamidine is known to cause renal failures owing to a necrosis of the
covering membrane. As the cerebral trunk and the kidneys seem to have to
have the same covering membrane, could it be an unknown side effect of
If you know that something similar has happened, or if you have an opinion,
I would be interested in hearing about it.
(Pentamidine is ordinarily used for the African trypanosomes -sleeping
sickness- and leishmaniose.)
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