long term potentiation

Stephan Anagnostaras stephan at nospam.ucla.edu
Mon Oct 26 20:30:10 EST 1998


In article <70qsg4$6me$1 at nnrp1.dejanews.com>, Hemidactylus at my-dejanews.com
wrote:

> In article <70nt33$8o0 at gap.cco.caltech.edu>,
>   hdvorak at cns.caltech.edu (Hannah Dvorak-Carbone) wrote:
> > In article <70lrmr$82g$1 at nnrp1.dejanews.com>, Hemidactylus at my-dejanews.com
> > says...
> >
> > [snip]
> >
> > >I am presently in search of references that critique the use of LTP as a
> > >model for vertebrate memory processing. Anybody know where I can find some
> > >good ones? Perhaps LTP is a good model for memory processes, but I
would like
> > >for someone here to give a serious critique.
> >
> > I've only just started reading this article, so I don't know how good it's
> > going to be, but you may want to look at Shors and Matzel 1997, Long-term
> > potentiation: What's learning got to do with it?  Behavioral and Brain
Sciences
> > 20(4):597-655.  For those of you not familiar with this journal, it's
actually
> > kind of cool.  They start with an article on a controversial topic,
then send
> > it out to experts in the field for comments, then publish the article along
> > with all the commentaries, so you get exposed to several sides of the
debate.
> > This may be just what you're looking for.
> >
> >
> 
> Thank you for the ref. I'm just starting to read two research articles that
> we'll be focusing on. Once I get a better handle on them, I'll post some
> thoughts and questions. They are:
> 
> Silva AJ, Stevens CF, Tonegawa S, and Wang Y. 1992. Deficient hippocampal
> long-term potentiation in alpha-calcium calmodulin kinase II mutant mice.
> Science (257): 201-206
> 
Sure, you should read this year's alpha CAM-KII papers as well, they are
in 1998 Science, both have Silva as a co-author.


> Wilson MA and Tonegawa S. 1997. Synaptic plasticity, place cells and spatial
> memory: study with second generation knockouts. Trends in Neurosciences (20):
> 102-106
> 
> I'll try to make it my library this weekend or next week to look up the
> journal article you mention above. -- Scott Chase (note followups at
> anthym at webtv.net)
> 
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