Rapid onset of action of Amineptine on depression
KPaulC at email.msn.com
Tue Aug 3 21:42:47 EST 1999
the worth of simple, unadorned, understanding:
i understand the 'costs' of speaking-up, Frank. i understand that my
'speaking-up' constitutes an 'affront' to those who 'hold power' over the
Science i'm trying to bring forward. i understand how it all works.
the 'difficulty', inherent' is that, if i fail to Honor Truth, the Science
would be, itself, so transformed by that failure that it'd, simultaneously,
cease to Exist.
what folks choose to do, in light of what i do, has nothing to do with what
i see, clearly, that i must do.
i will not fail.
beyond that, i Guard Free Will.
each person's Life is their's, alone, to Live.
the Sorrowful thing is with respect to those folks who've not yet even had
an opportunity to even begin to consider NDT's stuff, one way or the other.
but, if i acquiesced to the demands of self-interested folks who want me to
'veil' Truth, so as to 'cloak' what is, then there'd be no Truth for the
other folks to consider, would there?
so, the 'costs' are just 'the costs' of the gift i, long ago, chose to work
to present to folks.
i'm not being 'intransigent' for the sake of 'winning'.
to paraphrase Lincoln, 'i'm standing firm because i'm sure my feet are in
the right place.'
i'm mightily-tired from the work... but there's nothing of what folks refer
to as 'depression' in-me.
you'd laugh on seeing just how light my 'heart' is, in the knowledge that,
seeing Truth, i've only 'moved toward' it... despite 'the costs'.
if it was 'easy' it'd've been accomplished long ago.
if there's a need for such, please forgive me.
F. Frank LeFever wrote in message <7o85ee$o4a at dfw-ixnews4.ix.netcom.com>...
>Here I am, caught with my references down (again). I helped organize a
>conference for NYNG a few years ago, which included (among other
>things) a presentation of neuroimaging data which suggested that
>cognitive therapy (n.b.: I don't we can accept the simplistic equating
>of psychotherapy and "understanding"; v. infra) and pharmacotherapy
>(with a specific SSRI, I believe) produced similar changes in regional
>brain activation in those whose obsessive-compulsive disorder was
>Sorry, cannot for the life of me think of the guy's name. From
>California, I think... Anyway, this is not so esoteric; fairly
>well-known finding, so you should be able to search it out (via Medline
>I cite it just as another example (in addition to the one alluded to
>below) that there are as yet poorly explored and even less understood
>ways in which different therapies can not only result in similar
>outcomes behaviorally but may in some cases do so because of similar
>effects on the neuronal substrate of the disorder.
>This could provide a basis for independent (i.e. if monotherapy), or
>additive, or synergistic effects of different therapies.
>One caveat: I would not want to depend on cognitive therapy or any
>other non-physiological therapy for really severe depression. My
>impression (subject to correction, of course) is that studies showing
>comparable results for psychotherapy and pharmacotherapy do so with a
>different population: those with mild/moderate depression and/or those
>without "true" depression (e.g. with "reactive depression", "adjustment
>I almost wrote "pharmacotherapy or ECT" but realized it was not likely
>one would find enought subjects with mild/moderate depression
>More re regional differences in activation: we are all hoping for
>continued validation of TMS (transcranial magnetic stimulation), which
>not only offers the hope of less deleterious side effects than ECT, but
>in contrast to ECT's "sledge-hammer" or "shotgun" approach, only
>SLIGHTLY refined by the option of unilateral ECT (yes, yes, I know,
>seizure will spread to the other hemisphere, but it is applied
>unlaterally, and clearly has a unilateral bias in its immediate
>aftermath) offers the possibility of zeroing in more precisely on
>relevant brain SUB-regions--important both for understanding of the
>mechanisms of depression, and (we assume) for better treatments.
>F. Frank LeFever, Ph.D.
>New York Neuropsychology Group
>In <WFvp3.5039$B5.56894 at news1.rdc1.bc.home.com> "Sodah"
><sodah1 at NO-SPAMhome.com> writes:
>>It wouldn't hurt people to do a little research on the description of
>>_clinical_ depression, its nature and its modern treatment. For
>>is fairly well established that clinically depressed patients respond
>>to a combination of psychotherapy (i.e. "understanding") _plus_
>>antidepressant drug therapy, than to either therapy alone. What you
>>fancifully refer to as 'chemical short circuiting', happens to be in
>>practice, 'what works'
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