also tied to the force of contraction is frequency. the expression of
nNOS is different depending on the type of skeletal muscle (slow vs. fast
twitch) examined (sorry, can't remember which muscle type has more nNOS).
check out a recent article by Reiser et al., 1997 (Journal of Applied
Physiology, Vol.82 (4): 1250-1255) were able to induce nNOS via electrical
F. Frank LeFever wrote:
> Besides eNOS in the vasculature of muscles, nNOS is found within the
> muscle fibers themselves. Production of NO tends to decrease force of
> contraction. I believe "long ago"--as long ago as this very recent
> field allows--this negative ionotropic (right word???) function had
> been studied in heart muscle; more recently in skeletal muscle.
>> Why don't you do Medline search on (skeletal muscle) AND (NO or NOS)?
>> F. Frank LeFever, Ph.D.
> New York Neuropsychology Group
>> In <007701be4fb8$11e74ae0$411cfbd0 at default> rcb5 at MSN.COM ("Ron Blue")
> >Nitric Oxide Function in Skeletal Muscle??
> >I would to know more about this topic. Ron Blue