"Challenging", to say the least. Have known a few patients with
hydrocephaly (usually in context of spina bifida) and a few MS
patients, but am far from expert re either. Know something about
mild traumatic head injury. Will insert a comment or two below.
First: "probably" congenital? when noticed? when/how treated?
F. LeFever (v. infra)
In <7aoops$o76 at nnrp3.farm.idt.net> "rob" <22rdunca19 at idt.net> writes:
>>>After perusing this group a bit I have to say that you have some real
>loonies here. The sad thing is... theyre dumb as well. Oh well.
>>Now to my Q. I have hydrocephalus. (some may remember me from
>months ago.) I also have MS. How frequently are white matter lesions
>in hydro? How can I or my neuro tell the difference?
My impression is that white matter lesions are seen and/or
inferred primarily in tracts adjacent to ventricles, but I
invite correction from someone who knows. MS white matter
lesions might thereby be distinguished from them on basis of
I have been to far to
>many neuros and have received way to many conflicting opinions.
>>My last attack was in my pons. Can high icp affect that area? The LP
>pressure was high. But after calling the neuros at Barrows neuro
>said to never get another LP because of the possibility of coning.
>I also have the possibility of Arnold Chari malformation btw. Arent I
>pretty picture? It seems everything is on the cusp of being certain.
>>A little background I guess. I am/was perfectly normal. From others
>of view I suppose. Looks, brain, behavior, interests, IQ far above
>etc... But in retrospect its far to easy to correlate things that may
>unrelated. So I suppose some things may be attributable to the hydro,
>>Now, just how in the hell do I tell if I should have the third
>ventriculostomy? My MRIs have shown little difference in ventricle
>since the day of its discovery. (coming on 3 yrs, it was discovered
>by accident btw) I can understand periventricular lesions... but a
>in the pons?
>> If my hydro truly is stable, even with NO third aqueduct, I am
>go under the knife obviously. For me this is a conundrum. I have
>some cognitive deterioration, but still test well above norm on
>tests. I have even had one very well respected neurosurgeon tell me
>a tethered spinal cord and positioning can lead to a temp coning.
>>I have learned that neuro-opinions are like as&%#@$, everyone has one.
>not about to roll the dice, nor make the mistake of choosing one over
>other based on stature,behavior,certitude, etc... So I am left having
>make my own decisions. And I am the least qualified since I am not
>versed in neurology.
>>Here are the facts.
>I have moderate to sever longstanding hydrocephalus. Probably
>No prior headaches until car accident in march of 97.
Details? Head trauma? Loss of consciousness or no?
EEG or MRI data? SPECT?? Latency of headache development?
Other sequelae of accident?
I don't know of any hard data relating head trauma to MS
exacerbations or to exacerbation of preexisting
hydrocephaly, although effects of subarachnoid hemorrhage
might be relevant to latter.
I have, however, presented some speculative ideas about
possible neuroimmune mediation of some mild head trauma
sequelae--including headaches, fatigue, variable problems
with attention and/or memory lapses. Possible agents
include (but are not limited to) mast cells, which "should"
proliferate in some brain regions after brain trauma (and
are known to after some kinds of trauma). A role for
mast cells in demyelination of MS has been persuasively
argued (i.e. by MS researhers).
>3 exacerbations of (supposed) MS.
>few lesions. 3 in white matter, 1 in pons with a little bit into the
>matter (very little), possibly one in spine (t-9)
>SEVERE fatigue. not imagined, although I wish this was a question of
>sanity. (much easier to fix, I guess the resident loons arent so bad
>Basically I lost the right half of my body in my last attck and am
>I am on Interferon Beta 1A, famvir (because of hhv-6s possible role in
>amantadin for fatigue, etc...
>superior athlete (was)
>>This is getting long and I am getting tired so Ill leave you with this
>pose more questions and add to the confusion at a later time. Is
>more appropriate ng to post this to?
>>And BTW... the ignorance concernig animal cognition and empathy is
>me. I had never expected it from what seems like educated people.
>> As you well know, various problems (including cognitive
problems, including fatigue, etc.) can increase or decrease
during the course of MS.
Variable (day to day, moment to moment) symptomatology is
characteristic of mild head trauma (postconcussion
syndrome) as well>
Finally, is it possible that interferon itself accounts for
some cognitive and/or vegetative (fatigue) symptoms?
Sorry I can't be more "definitive"!
F. Frank LeFever, Ph.D.
New York Neuropsychology Group