Just to make it explicit, if I understand Dr. Vickery correctly, do
citation search forward--using _Science_Citation_Index_ !
(I love to spread the gospel re SCI, a neglected or sometimes misused
wonderful database)
OR, if there is an alternative database for this kind of search, I'm
interested in learning about it; every little bit helps.
F. LeFever
In <36D1FC5B.DCBDB484 at unsw.edu.au> Richard Vickery
<Richard.Vickery at unsw.edu.au> writes:
>>Wookie wrote:
>>> LTP [long term potentiation] which increases synaptic strength
(larger
>> EPSC's which leads to larger EPSP's)
>> and LTD [Long Term Depression] that decreases synaptic strength.
>>> In LTP the post-synaptic [Ca2+] rises very high (up to 5 micromolar)
>> in LTD the post-synaptic [Ca2+] rises only slightly [lower than 1
>> micromolar].
>> So there you have it, these differences in concentration determine
>> what enzymes are used.
>>> How can this difference in concentration alone account for the
choice
>> of enzymes?
>>Check out
>J. Lisman 1989
>PNAS 86: 9574-9578
>A mechanism for the Hebb and anti-Hebb processes underlying
>learning and memory.
>>You could do a citation search forward from there if you need to.
>>--
>Dr Richard Vickery
>School of Physiology & Pharmacology, UNSW, Australia, 2052
>ph. 61 2 93851676, fax 61 2 93851059
>http://www.med.unsw.edu.au/Physiology/School/staff/vickery/Welcome.htm
