Braindamage due to lack of oxygen.

F. Frank LeFever flefever at
Mon Mar 29 21:59:21 EST 1999

I stand corrected (I'm no chemist, as you can see!).

Meanwhile, any ideas on the NO angle?

F. LeFever

In <7dn7n3$8oe$1 at oravannahka.Helsinki.FI>
dag.stenberg at writes: 
>F. Frank LeFever <flefever at> wrote:
>> What some people inhale for recreational purposes is, I believe, NO2
>> (not N2O), i.e. nitrous oxide.  I believe there has been some
>> published that suggestts long-term abuse of this gas may cause brain
>> damage.  I believe tthe interpretation has been that this is due to
>> hypoxia, but it occurs to me that the (as yet little studied)
>> consequence of increased brain levels of NO (nitric oxide) might
>> play a role...
>Actually N2O, not NO2. It is necessary to mix at least 15% oxygen with
>as hypoxia will otherwise occur. Of course, a short sniff of pure N2O
>not create severe hypoxia, and as long as someone takes the pure N2O
>in time, there should not be any brain damage. Possible (individual) 
>euphoric effects do not require simultaneous hypoxia.
>Dag Stenberg

More information about the Neur-sci mailing list