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On Sun, 14 Nov 1999 16:22:55 -0000, GORANOV <Bojidar.Goranov at ncl.ac.uk> wrote, in bionet.neuroscience: ^Could anyone tell me if the hypothalamus is the major producer of ^Beta-endorphin for the brain? The periaquaductal grey matter produces more, but I believe its location of action is more spinal cord than brain.