RESEARCH POSITIONS AVAILABLE

WJ DE GRIP wdegrip at baserv.uci.kun.nl
Mon Aug 14 10:08:34 EST 2000



POSTDOCTORAL AND PhD POSITIONS IN PROTEIN EXPRESSION AND STRUCTURAL 
BIOLOGY

Three positions are available in the Institute of Cellular Signalling
(ICS), University of Nijmegen, The Netherlands, dept. Biochemistry,
research group G-protein coupled receptors (GPCR). Strongly motivated
individuals are sought to work in a thriving, collaborative research
environment.
  1.	A postdoctoral position is available to further develop functional
expression and stable-isotope labeling of GPCR in the recombinant
baculovirus expression system. Large-scale culture and purification should
produce sufficient material for structure/function analysis (FT-IR, NMR).
The applicant should have a Ph.D. in Biochemistry or Molecular Biology,
with research experience in cell culture. Expertise in protein
purification and characterization is recommended.
  2.	A Ph.D. position is available that will focus on
structure/function analysis of recombinant GPCR by FT-IR difference
spectroscopy and molecular modeling. 
The applicant should have a master's degree or equivalent level of
education with a sound training in Biophysics or Biophysical Chemistry and
with a strong interest in biomolecular research. Preference will be given
to candidates with expertise in theory and practice of spectroscopic
analysis.
  3.	A third position is available, that can be filled either as a
postdoctoral project or as a graduate project. This project will
concentrate on structure/function studies of visual pigments. Baculovirus
expression and purification will be optimized to allow functional analyses
(photochemistry, signal transduction) and structural studies (solid-state
NMR in collaboration with Leiden university).
This applicant should have a strong background in molecular biology and
cell culture. Expertise in protein purification and characterization is
recommended. 
	Interested candidates can find further information at the web-site
of the ICS (http://surf.to/ICS) in the section jobs/biochemistry.
Alternatively, inquiries can be made at the address below.
	The ICS offers state-of-the-art facilities for (training in)
recombinant DNA, biochemical, cell-biological and biophysical research.
The University of Nijmegen - Medical Center is an Equal Employment and
Equal Opportunity Employer. Women are encouraged to apply. 
	




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	Prof. dr. Willem J. DeGrip
	Dept. Biochemistry, UMC-160
	Institute of Cellular Signalling
	University of Nijmegen
	P.O. Box 9101			tel.  xx31-24-3614263/3614259
	6500 HB Nijmegen		fax.  xx31-24-3540525 
	The Netherlands			email.  wdegrip at baserv.uci.kun.nl 
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