an ALS Hypothesis

Andrew K Fletcher gravitystudy at hotmail.com
Mon Feb 7 13:39:02 EST 2000


Hi Bill, thank you for your reply.

What I am looking for is to see if the "amyloid precursor protein or APP" is
part of solidified myelin and cerebrospinal fluid. If the make up is the
same it might lead to understanding how these plaques develop. For example,
a scab results from blood, so presumably it must have the same compound base
as blood.

I don't know who to approach with this, perhaps you might be able to suggest
an avenue.

Kind regards

Andrew




Bill Skaggs <skaggs at bns.pitt.edu> wrote in message
news:m7zotdzz99.fsf at skaggs.bns.pitt.edu...
> "Andrew K Fletcher" <gravitystudy at hotmail.com> writes:
>
> > Has anyone any knowledge of the make up of the scar tissue in the
plaques
> > found in neurological conditions. In laypersons terms preferably.
>
> The plaques seen in Alzheimer's Disease are made of a substance called
> amyloid, which is a fragment of a protein called, straightforwardly
> enough, amyloid precursor protein or APP.  (I'm sorry, there is no
> layperson's term for "amyloid".)
>
> -- Bill
>





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