Neurotransmitters

Richard Norman rsnorman at mediaone.net
Fri Jan 28 18:30:02 EST 2000


Virtually any neurophysiology, neurochemistry or
pharmacology book will have lists of neurotransmitters.

For example: Kandel et al (Principals of Neural Science,
4th Ed, McGraw Hill, 2000) p. 281 lists
  Small molecule transmitter substances:
      Acetylcholine, Biogenic amines (dopamine,norepinephrine,
       epinephrine, serotonin, histamine), Amino acids (gamma-
       amino butyric acid, glycine, glutamate).

 Then, on p. 288 it lists some 46 neuroactive mammalian brain
peptides.

However, it really is not possible to list a "function" associated
with a neurotransmitter.  For example, in the periphery ACh
is involved in stimulating skeletal muscle and activating sympathetic
and parasympathetic ganglia.  It also frequently inhibits smooth and
cardiac muscle.  In the CNS it has complex effects, depending on
exactly what cells in what pathways it acts.  Similarly for the other
transmitters.  Glutamate and GABA are widely distributed in many
areas of the brain.

You probably are referring to the way some people attribute a
particular neural function to things like dopamine or serotonin.  The
fact is that the chemical is just a signal sent from one cell to another.
The significance of the signal is entirely dependent on the pathway
and the particulars of the cell that receives the signal and how it
responds to the signal.


Patrick & Sangeeta Bishop <psbishop at worldnet.att.net> wrote in message
news:389216F4.7AB05A39 at worldnet.att.net...
> Greetings,
>
> Is anyone aware of a comprehensive information resource regarding
> neurotransmitters and the function of each, i.e., what each
> neurotransmitter regulates.
>
> Thanks in advance!
>
> Patrick Bishop
>






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