sam-e causes brain damage?

larryhoover at my-deja.com larryhoover at my-deja.com
Tue Oct 10 07:58:25 EST 2000


In article <8rujge$464$1 at bob.news.rcn.net>,
  "eric" <errock at rcn.com> wrote:
> note the rigidity and dyspnoea following intravaneous admin.
>
> Reproductive toxicity studies of ademetionine.
>
at dosages of 0, 100, 200
> and 400 mg/kg/d SAMe ion by subcutaneous or intravenous
administration.

Eric, please try to consider the doseage regime before you leap to
conclusions. For a human of 70 kg body weight (154 lbs.), even the
lowest treatment dose amounts to 7000 mg/day. IV administration also
introduces an unknown variable, as oral dosing may affect the
pharmacokinetic parameters. This study only shows that injecting the
equivalent of perhaps 28000 mg/day of SAMe may have deleterious
effects. That's not hard to imagine, is it?

Regards,
Larry


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