Cloning for spinal research.

Robert Clark rgclark at MailAndNews.com
Fri Apr 27 03:58:24 EST 2001


Found the attached post dating from 1997 by searching on 
groups.google.com. I've heard that neural cells have been 
produced by using embryonic stem cells. Does anyone know if the 
method of cloning neurons by implanting the nucleus in peripheral 
nerve cells has been used?

 There is opposition to cloning people on ethical grounds and 
also because of the large numbers of failures you get before a 
success and many of the successes happen to have physical problems. 
However, the second method of generating neurons by cloning someone 
and only allowing the clone to develop to the embryo stage would 
not seem to have these same problems. Many embryos are already made 
and discarded in in vitro fertilization. And you would not be 
concerned about the health problems of a full grown individual.


     Bob Clark


*************************************************************
From: Robert Clark (rclark at op.net)
Subject: Applications of the Cloning Method II 
Newsgroups: sci.bio.technology, alt.bio.technology.cloning, 
bionet.microbiology, sci.bio.microbiology, sci.bio.misc, 
sci.bio.technology, alt.med.cure-paralysis, sci.med
Date: 1997/04/17

 In a prior post to sci.bio.technology, I suggested that the
method the Roslin researchers used may be applicable to treating 
brain and spinal cord injuries. The idea being that the embryonic
cell only needed the surrounding embyonic cell material, not its 
original embyonic nucleus to divide and differentiate as a normal 
embryo.
 I suggested that the nucleus of a CNS neuron be implanted into
the type of nerve cell that does have the capacity to regenerate,
generally peripheral nerve cells, to see if the result is able to 
generate copies of the CNS neuron.
 There is, however, a more direct way to generate copies of CNS
neurons. That is to duplicate the Roslin method for the subject
whose CNS cells are to be replaced, except remove the developing 
embryo once the CNS neurons have sufficiently differentiated.
 How long does it take for example for spinal cord neurons to
reach the stage where they are pretty much set in their adult form?


    			Bob Clark
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