Migraine question

MS marshmallow5 at yahoo.com
Wed Feb 7 21:15:50 EST 2001

I have to disagree about the mechanism of aspirin. Aspirin reduces pain by
inhibition of prostaglanden E2, which sensitizes nociceptive afferents.
However, you might have had caffeine in mind, which is a vasoconstrictor and
is used to treat migraine, which agrees with what you are saying.

Why is it that vasodilation causes the pain of a migraine however?

Ashish Ranpura <aranpura at mindspring.com> wrote in message
news:9fr38tsc2l57h08o96k2ceqo02ccq9512o at 4ax.com...
> Never one to back down from pure, uninformed speculation: the normal
> variety of headache results from vasodilation, which is why
> vasoconstrictors like aspirin can relieve the pain. I've no idea
> whether migranes follow a similar pattern.
> But a related question to the group: I have recently heard that some
> migrane sufferers find regular magnesium supplements effective in
> reducing the incidence of migrane headaches. Any reasons why magnesium
> might help?
> ---Ashish Ranpura.

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