Migraine question

James Teo james at teoth.fsnet.co.uk
Thu Feb 8 18:49:10 EST 2001

On Wed, 07 Feb 2001 16:57:45 -0800, Ashish Ranpura
<aranpura at mindspring.com> wrote:

>Never one to back down from pure, uninformed speculation: the normal
>variety of headache results from vasodilation, which is why
>vasoconstrictors like aspirin can relieve the pain. I've no idea
>whether migranes follow a similar pattern.

Er, aspirin isn't a vasoconstrictor, it acts by blocking prostaglandin
synthesis. It relieves pain by reducing the amount of inflammatory
mediators, particularly in inflammatory diseases. It is not clear how
it helps some migraine sufferers. 

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